# Rare Instances of Culture-Positive Dengue-Related Panophthalmitis: A Case Series

**Authors:** Chaitanya Modgil, Renu Magdum, Iqra Mushtaq

PMC · DOI: 10.7759/cureus.63948 · Cureus · 2024-07-06

## TL;DR

This paper reports three rare cases of severe eye inflammation caused by dengue fever in India, highlighting the importance of early diagnosis and treatment.

## Contribution

The novelty lies in documenting rare instances of panophthalmitis linked to dengue, emphasizing the need for awareness among healthcare providers.

## Key findings

- Three patients with dengue developed severe panophthalmitis requiring evisceration surgery.
- Ocular complications in dengue, though rare, can be severe and require prompt diagnosis.
- Aggressive medical management failed to prevent extreme ocular deterioration in these cases.

## Abstract

Panophthalmitis is an exceptionally rare but severe ocular complication of dengue fever, which is currently a significant health concern in parts of India. It is a purulent inflammation encompassing all structures of the globe (choroid, retina, vitreous fluid, aqueous fluid, cornea, sclera, and conjunctiva) along with surrounding orbital and periorbital structures. This case series highlights the occurrence of panophthalmitis in three patients diagnosed with dengue, who were aged 35, 50, and 75 years. Despite aggressive medical management, including intravenous antibiotics, the patients were ultimately scheduled for evisceration surgery due to the extreme severity of the condition. Healthcare providers must be aware of the potential ocular complications in dengue cases and diagnose them promptly. While ocular involvement in dengue is rare, this case series emphasizes the importance of recognizing ocular manifestations in dengue patients, as early diagnosis and prompt intervention can prevent severe complications.

## Linked entities

- **Diseases:** dengue fever (MONDO:0005502), panophthalmitis (MONDO:0006884)

## Full-text entities

- **Diseases:** ocular involvement (MESH:C565423), Panophthalmitis (MESH:D010202), purulent inflammation (MESH:D007249), Dengue (MESH:D003715)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11299046/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11299046/full.md

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Source: https://tomesphere.com/paper/PMC11299046