# Antepartum hemorrhage due to placenta previa with autologous transfusion: A case report

## TL;DR

This case report shows that autologous blood transfusion can improve outcomes for a woman with placenta previa during a C-section, reducing risks compared to traditional blood transfusions.

## Contribution

The paper highlights the benefits of autologous transfusion in managing antepartum hemorrhage due to placenta previa.

## Key findings

- Autologous transfusion improved postoperative hemodynamics and blood parameters like RBC, platelets, HCT, and Hb.
- It reduced transfusion-related risks such as infections and immunosuppression.
- Autologous transfusion cannot fully replace homologous transfusion but offers safer alternatives for rare blood types.

## Abstract

Bleeding during pregnancy or during childbirth can cause significant morbidity and mortality for the mother and baby, this can be overcome by performing a caesarean section (C-section) and blood transfusions. Although blood transfusions can save lives, there is a risk such as transfusion reactions, transmission of infection, and anaphylaxis. Giving autologous blood transfusion can reduce the risk of these events. This case report aims to investigate the advantages of autologous blood transfusion in managing the patient's hemodynamic status compared to homologous blood transfusion.

A 21-year-old female (G2P1A0) with antepartum hemorrhage (APH) due to placenta previa underwent emergency C-section with intrauterine device installation and hysterectomy. The patient received an autologous transfusion to improving the hematocrits and hemoglobin within 30 min. Autologous transfusion provided routine postoperative hemodynamics, electrolytes, and blood stability. However, it could not completely replace homologous transfusion.

Autologous transfusion reduces transfusion response, infection risk, and immunosuppression. Consequently, it reduces the need for allogenic blood supplies and enables safer transfusion for people with rare blood types and various auto-antibodies.

Autologous transfusions may provide better outcomes in C-section surgery for APH patients due to placenta previa. Thus, we recommend the use of autologous over homologous transfusion. Further research is required to compare them to a large population.

•Reinfusion of blood or blood components into the same person from whom they were taken is known as autologous blood transfusion.•Placenta previa occurs with an incidence of 0.3-0.5% of all pregnancies. Placenta previa is also found in 20% of APH which can cause death in mothers and newborn.•Autologous transfusion provided better postoperative C-section and increased RBC, Platelets, HCT, and Hb compared to homologous transfusion

Reinfusion of blood or blood components into the same person from whom they were taken is known as autologous blood transfusion.

Placenta previa occurs with an incidence of 0.3-0.5% of all pregnancies. Placenta previa is also found in 20% of APH which can cause death in mothers and newborn.

Autologous transfusion provided better postoperative C-section and increased RBC, Platelets, HCT, and Hb compared to homologous transfusion