# A Successful Pregnancy Outcome Using Laser-Assisted Hatching and Platelet-Rich Plasma Perfusion in Advanced Maternal and Paternal Age: A Case Report

## TL;DR

A couple with long-term infertility achieved a successful pregnancy using personalized treatments involving platelet-rich plasma and laser-assisted hatching.

## Contribution

This case demonstrates the potential of PRP and LAH in overcoming infertility in older parents with a history of failed IVF.

## Key findings

- PRP treatment improved endometrial thickness, aiding embryo implantation.
- Laser-assisted hatching successfully facilitated embryo implantation after multiple ART failures.
- Personalized interventions led to a successful pregnancy in a couple with advanced parental age.

## Abstract

Infertility affects millions globally, with advanced parental age posing a significant risk. This case report details a couple who experienced secondary infertility for 12 years. Following multiple unsuccessful attempts at assisted reproductive technology (ART), a personalized treatment regimen involving platelet-rich plasma (PRP) perfusion and laser-assisted hatching (LAH) resulted in a successful pregnancy. Diagnostic evaluations identified specific reproductive challenges, leading to tailored interventions. A positive pregnancy outcome was achieved after PRP treatment enhanced endometrial thickness and LAH facilitated embryo implantation. This case highlights the importance of individualized treatment strategies in infertility management and proves the potential efficacy of PRP and LAH in overcoming recurrent implantation failure. Further research is needed to explain the roles of PRP and LAH in improving pregnancy outcomes, especially in older parents and couples with a history of failed in vitro fertilization (IVF) treatments.