# Exploring the Pathological Journey of Superficial Spreading Squamous Cell Carcinoma of the Cervix Into the Endometrium

## TL;DR

This paper describes a rare case of cervical cancer spreading into the endometrium, highlighting its unique pathological features and diagnostic challenges.

## Contribution

The study presents a rare case of superficial spreading cervical SCC extending into the endometrium, emphasizing its under-recognized clinical significance.

## Key findings

- The tumor extended superficially into the endometrium, replacing glands rather than invading the stroma.
- Carcinoma in situ changes were observed in the vagina, supporting the diagnosis of cervical SCC extension.
- Immunohistochemical testing confirmed the tumor was an extension of cervical SCC, not a primary endometrial carcinoma.

## Abstract

The superficial extension of cervical squamous cell carcinoma (SCC) into the endometrium by replacing the endometrial glands is rare, as it normally spreads by invading the stroma or by lymphatic invasion. We present a case of a postmenopausal female complaining of vaginal discharge followed by vaginal bleeding. Microscopy showed a superficial spreading SCC of the cervix extending superficially into the endometrium with focal myometrial invasion. Carcinoma in situ changes were observed in the vagina. Based on the Fluhmann criteria and ancillary immunohistochemical testing, it was concluded to be an extension of cervical SCC and not primary endometrial carcinoma. The importance of this entity has not been given because of its low incidence.