# A Case of Digital Papillary Carcinoma Arising on the Toe in a Young Female

**Authors:** Lily Park, Jennifer Wong

PMC · DOI: 10.7759/cureus.63776 · Cureus · 2024-07-03

## TL;DR

A teenage girl developed a rare cancer on her toe that was initially misdiagnosed, highlighting the need for biopsies in unusual skin growths.

## Contribution

This case highlights the diagnostic challenge of distinguishing benign and malignant skin lesions through clinical and histopathological findings.

## Key findings

- Digital papillary carcinoma can present in young patients and may be misdiagnosed as benign lesions.
- Prior excisions without biopsy can lead to recurrence of aggressive skin neoplasms.
- Biopsy is crucial for accurate diagnosis of skin lesions of unknown origin.

## Abstract

Syringocystadenoma papilliferum is a rare benign adnexal hamartoma that is often associated with the nevus sebaceous of Jadassohn. It usually presents on the scalp and malignant transformation is rare. Here we present a case of digital papillary carcinoma on the toe of a teenage girl. The lesion recurred after two prior excisions without biopsy. The biopsy was read as a syringocystadenoma papilliferum with concerns for aggressive digital papillary adenocarcinoma, highlighting the importance of biopsy with excisions of neoplasms of unknown etiology.

## Linked entities

- **Diseases:** syringocystadenoma papilliferum (MONDO:0019392), nevus sebaceous of Jadassohn (MONDO:0008097), digital papillary carcinoma (MONDO:0044789), aggressive digital papillary adenocarcinoma (MONDO:0044789)

## Full-text entities

- **Diseases:** neoplasms (MESH:D009369), digital papillary adenocarcinoma (MESH:D000231), nevus sebaceous (MESH:D054000), Digital Papillary Carcinoma (MESH:D002291), adnexal hamartoma (MESH:D006222), Syringocystadenoma papilliferum (MESH:D000074009)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11296958/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11296958/full.md

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Source: https://tomesphere.com/paper/PMC11296958