# DMP-1 expression in alveolar bone socket following Anredera cordifolia (Ten.) Steenis treatment: A histological study

## TL;DR

This study shows that a gel made from Anredera cordifolia boosts DMP-1 protein in rat alveolar bone sockets after tooth extraction.

## Contribution

The novel finding is that Anredera cordifolia gel significantly increases DMP-1 expression in healing alveolar sockets.

## Key findings

- DMP-1 expression was significantly higher in the treatment group on day 8 and 15.
- A. cordifolia gel stimulated DMP-1 expression compared to the control group.
- Histological analysis confirmed significant differences under 400x magnification.

## Abstract

The study aimed to ascertain how Anredera cordifolia (Ten.) Steenis Gel affects the expression of protein dentin matrix protein-1 (DMP-1) in alveolar Wistar rats after tooth extraction.

Rats were given A. cordifolia (Ten.) Steenis gel was in the socket after tooth extraction, and then the wound was sutured. The rats were sacrificed for 8 and 15 days following tooth extraction. The results on the 8th and 15th days demonstrate that the expression of DMP-1 in the treatment group is significantly higher than in the control group.

Expression of DMP-1 in the socket after tooth extraction on days 8 and 15 with a 400x magnification light microscope in both of the A. cordifolia (Ten.) Steenis gel treatment groups showed significant differences compared to the control group.

The use of A. cordifolia (Ten.) Steenis gel can stimulate DMP-1 expression in alveolar bone after tooth extraction.