# Pioneering robotic-assisted surgery for insulinoma during pregnancy: The first case report and literature review

## TL;DR

This paper reports the first successful robotic surgery to treat insulinoma in a pregnant woman, showing it can be safe for both mother and baby.

## Contribution

The paper presents the first case of robotic enucleation for insulinoma during pregnancy, demonstrating a novel surgical approach.

## Key findings

- Robotic enucleation was successfully performed at week 18 of gestation for a 2-cm pancreatic insulinoma.
- The patient experienced relief from hypoglycemic episodes and delivered a healthy baby without complications.

## Abstract

Insulinoma during pregnancy is a rare condition with vague clinical symptoms, making diagnosis challenging. The standard treatment for insulinoma is surgical tumor removal, preferably using a minimally invasive method. However, there have been no recorded examples of employing a robotic platform in pregnant women with insulinoma. In this report, we present the first successful case of robotic enucleation for insulinoma during pregnancy.

A 30-year-old pregnant woman presented with recurrent hypoglycemic symptoms throughout her first trimester that were relieved by food intake. After confirming endogenous hyperinsulinemia, an abdominal magnetic resonance imaging scan was performed to locate the tumor. A well-defined 2-cm mass was found in the pancreatic body. Robotic enucleation was performed at week 18 of gestation, and the patient experienced relief from hypoglycemic episodes postoperatively. Her blood glucose levels returned to normal, and she had an uneventful pregnancy. The patient eventually delivered a healthy baby via cesarean section without any complications.

For a subset of pregnant individuals with insulinoma, a minimally invasive approach as robotic-assisted surgery is safe and feasible. This innovative technique has the potential to both mothers and fetuses.