# Remission With Radiation Therapy in Primary Tongue Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report

**Authors:** Masaki Tobikawa, Jun-ichi Saitoh, Tatsuji Mizukami, Kentaro Yamagishi, Mayu Takaichi

PMC · DOI: 10.7759/cureus.63703 · 2024-07-02

## TL;DR

A rare case of tongue MALT lymphoma was successfully treated with radiation therapy, resulting in complete metabolic response.

## Contribution

This case report adds to the limited literature on tongue MALT lymphoma and demonstrates the effectiveness of radiation therapy.

## Key findings

- A 79-year-old woman with tongue MALT lymphoma achieved complete metabolic response after radiation therapy.
- Only six cases of tongue MALT lymphoma have been reported in the literature.
- Radiation therapy at 30.6 Gy in 17 fractions was effective in treating this rare lymphoma.

## Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma arising from the tongue is a rare pathologic condition for which a standard treatment mode has not been established. This disease represents a low-grade lymphoma frequently found in the stomach but rarely in the lymphoid tissue of the tongue. Only six cases that have been reported could be retrieved. We present the case of a 79-year-old woman who manifested with a mass on her tongue. A biopsy of the mass confirmed a diagnosis of MALT lymphoma. Radiation therapy of 30.6 Gy in 17 fractions was performed, and a complete metabolic response was achieved.

## Linked entities

- **Diseases:** MALT lymphoma (MONDO:0007650)

## Full-text entities

- **Diseases:** MALT lymphoma (MESH:D018442), lymphoma (MESH:D008223)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11293890/full.md

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Source: https://tomesphere.com/paper/PMC11293890