# Ovarian Sertoli-Leydig Cell Tumors in a Three-Year-Old Child

## TL;DR

A rare ovarian tumor causing virilization in a three-year-old girl is reported, highlighting the importance of considering this condition in young girls with similar symptoms.

## Contribution

This case report presents the youngest known case of ovarian Sertoli-Leydig cell tumor, expanding clinical awareness for early diagnosis.

## Key findings

- Ovarian Sertoli-Leydig cell tumors can present in very young children with virilization and abdominal mass.
- Early diagnosis and histological evaluation are crucial for determining prognosis and treatment.
- This case expands the known age range for such tumors and emphasizes the need for prompt clinical evaluation.

## Abstract

Ovarian Sertoli-Leydig cell tumors (SLCT) are extremely rare malignant tumors deriving from the sex cord stroma. An abdominal mass and a virilization syndrome dominate the clinical symptoms. This particular tumor poses diagnostic and therapeutic problems. Prognosis depends on staging (the International Federation of Gynecology and Obstetrics (FIGO)/tumor, node, metastasis (TNM)) and differentiation. The treatment is surgical, combined with adjuvant chemotherapy in certain cases.

We report the case of a three-year-old girl admitted to our department for signs of virilization with an abdominal mass. The literature does not contain any reports of a younger case. Ovarian SLCTs should be considered in every girl presenting with signs of virilization and a lower abdominal mass. The prognosis and management depend on the results of the histological analysis and extension evaluation in order to define therapeutic management.