# Composite eosinophilic solid and cystic renal cell carcinoma and clear cell renal cell carcinoma: a rare case report and literature review

## TL;DR

A rare case of two kidney cancers, ESC-RCC and ccRCC, occurring together in one kidney is reported, highlighting the importance of imaging and pathology for diagnosis.

## Contribution

This case report adds to the limited literature on composite renal tumors involving ESC-RCC and ccRCC.

## Key findings

- A 48-year-old male was diagnosed with ESC-RCC and ccRCC in the same kidney.
- Imaging and postoperative pathology confirmed the composite tumor diagnosis.
- The patient showed no tumor recurrence during a 12-month follow-up.

## Abstract

Eosinophilic solid and cystic renal cell carcinoma (ESC-RCC) is a novel subtype of renal cell carcinoma characterized by its relatively low incidence and indolent behavior. We report a rare case of ESC-RCC concurrent with clear cell renal cell carcinoma (ccRCC) in a single kidney.

A 48-year-old male, was found to have a mixed echogenic mass in the left kidney during a physical examination. He has no history of hematuria and flank pain. An abdominal CT scan revealed a 3.0 * 1.9 * 2.5 cm3 mass with unclearly bordered at the lower pole of the left kidney. Abdominal MRI showed two nodules of different sizes in the left kidney, suggesting the possibility of a tumor. The patient underwent a subtotal nephrectomy, and the postoperative pathological results indicated ESC-RCC combined with ccRCC. The patient recovered well without tumor recurrence during the 12-month follow-up.

We reported a case of renal composite tumors, comprising the rare ESC-RCC and the more common ccRCC. Imaging combined with postoperative pathological examination is crucial for the definitive diagnosis of these rare tumors.