# An Anaphylactic Encounter With Ferric Gluconate Infusion: A Case Report

**Authors:** Mohamed A Ebrahim, Eli A Zaher, Tatev Aloyan, Sharathshiva Valaiyaduppu Subas

PMC · DOI: 10.7759/cureus.63209 · Cureus · 2024-06-26

## TL;DR

A 71-year-old woman had a severe allergic reaction to a type of intravenous iron treatment, emphasizing the need for caution with such therapies.

## Contribution

Reports a rare anaphylactic reaction to sodium ferric gluconate infusion in a patient with iron deficiency anemia.

## Key findings

- A 71-year-old female experienced anaphylaxis during sodium ferric gluconate infusion.
- Prompt treatment with epinephrine and steroids led to rapid recovery.
- The case highlights the risk of hypersensitivity to intravenous iron formulations.

## Abstract

Iron deficiency anemia (IDA) is a prevalent condition globally, often necessitating intravenous iron therapy. We present a case of a 71-year-old female with IDA who experienced a severe anaphylactic reaction shortly after commencing a sodium ferric gluconate complex infusion. Prompt cessation of the infusion and administration of epinephrine with steroids led to rapid recovery. This case underscores the importance of recognizing and managing rare yet potentially life-threatening hypersensitivity reactions to intravenous iron formulations, highlighting the need for vigilance among healthcare providers.

## Linked entities

- **Chemicals:** ferric gluconate (PubChem CID 656646), epinephrine (PubChem CID 838), steroids (PubChem CID 139082353)
- **Diseases:** iron deficiency anemia (MONDO:0001356), anaphylaxis (MONDO:0100053)

## Full-text entities

- **Diseases:** hypersensitivity (MESH:D004342), IDA (MESH:D018798), An Anaphylactic Encounter (MESH:D000707)
- **Chemicals:** epinephrine (MESH:D004837), iron (MESH:D007501), steroids (MESH:D013256), Ferric Gluconate (MESH:C035552)

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11281878/full.md

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Source: https://tomesphere.com/paper/PMC11281878