New drug-delivery balloon catheter for easy and fast injection of triamcinolone after esophageal endoscopic submucosal dissection
Takashi Hirose, Hiroyuki Shibata, Kazuhiro Furukawa, Takeshi Yamamura, Takuya Ishikawa, Masanao Nakamura, Hiroki Kawashima
Abstract
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TopicsEsophageal Cancer Research and Treatment · Gastric Cancer Management and Outcomes · Esophageal and GI Pathology
Esophageal endoscopic submucosal dissection (ESD) is a very common and useful endoscopic treatment for superficial esophageal cancer 1 . The most common delayed adverse event of esophageal ESD for extensive lesions is stenosis 2 . Local injection of triamcinolone is the most common form of stenosis prevention 3 , and the method using a needle is a rather complicated and time-consuming procedure. A new drug-delivery balloon catheter is a device with multiple micro holes on its surface that eject fluid from the balloon when the balloon pressure rises.
A man in his 60s underwent ESD for semiperipheral superficial esophageal cancer in the upper thoracic esophagus ( Fig. 1 ). The resected pathology was squamous cell carcinoma, and curative resection was obtained. After resection, the mucosal defect extended to 7/8 of the circumference ( Fig. 2 ), and triamcinolone 40 mg was injected into the post-treatment ulcer using the new drug-delivery balloon catheter ( Video 1 ).
Semiperipheral superficial esophageal cancer in the upper thoracic esophagus.
After endoscopic resection, the mucosal defect extended to 7/8 of the circumference.
After resection, the mucosal defect extended to 7/8 of the circumference, and triamcinolone 40 mg was injected into the post-treatment ulcer using the new drug-delivery balloon catheter.Video 1
The procedure was completed in only a few minutes, and was very safe and simple. Post-procedure observation showed that triamcinolone was injected evenly and firmly into the ulcer ( Fig. 3 ).
Post-procedure observation showed that triamcinolone was injected evenly and firmly into the ulcer.
A new drug-delivery balloon catheter allows for safe, simple, and quick triamcinolone injection after esophageal ESD.
Endoscopy_UCTN_Code_TTT_1AO_2AG_3AD
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- 1Inoue H Minami H Kaga M Endoscopic mucosal resection and endoscopic submucosal dissection for esophageal dysplasia and carcinoma Gastrointest Endosc Clin N Am 2010202534, v-vi 10.1016/j.giec.2009.08.00519951792 · doi ↗ · pubmed ↗
- 2Ishihara R Prevention of esophageal stricture after endoscopic resection Dig Endosc 20193113414510.1111/den.1329630427076 · doi ↗ · pubmed ↗
- 3Miyake M Ishihara R Matsuura N Predictors of stricture after non-circumferential endoscopic submucosal dissection of the esophagus and single-dose triamcinolone injection immediately after the procedure Gastrointest Endosc 20239817017710.1016/j.gie.2023.03.01736990127 · doi ↗ · pubmed ↗