# Effects of Chronic Barley Consumption on Upper Respiratory Tract Symptoms in Japanese Healthy Adults: A Randomized, Parallel-Group, Controlled Trial

**Authors:** Risa Araki, Chiaki Ishikawa, Tomomi Kawasaki, Toshiro Kobori, Toshihiko Shoji, Yoshiharu Takayama

PMC · DOI: 10.3390/nu16142298 · 2024-07-17

## TL;DR

Eating cooked waxy barley daily for 8 weeks reduced nasal symptoms and improved mood in healthy Japanese adults compared to white rice.

## Contribution

This is the first randomized trial showing that barley containing β-glucan alleviates upper respiratory symptoms and improves mood.

## Key findings

- Barley reduced sneezing and fatigue compared to white rice.
- Nasal symptoms like runny nose and plugged nose were less severe in the barley group.
- Barley improved mood by reducing tension and anguish scores.

## Abstract

β-(1,3/1,4)-glucan is a major component of cereal grains, such as oats and barley. In this study, we investigated the effects of cooked waxy barley, which contains β-(1,3/1,4)-glucan, on upper respiratory tract physical symptoms and mood status by performing a randomized, parallel-group, comparative trial. The primary outcome was assessed using the Wisconsin Upper Respiratory Symptom Survey-21 and Profile of Mood States second edition. Twenty-seven healthy Japanese adult participants were supplemented with 100 g of cooked waxy barley (containing 1.8 g of β-glucan) or 100 g of cooked white rice daily for 8 weeks. Participants receiving cooked waxy barley reported a reduction in cumulative days of sneezing (p < 0.05) and feeling tired (p < 0.0001) compared with the control group. After the intervention period, there were significantly less severe nasal symptoms, such as runny nose, plugged nose, and sneezing (p < 0.05), and a significantly greater reduction of the Tension-Anguish score (p < 0.05) in the barley group than in the control group. This study suggests that supplementation of cooked waxy barley containing β-(1,3/1,4)-glucan prevents or alleviates nasal upper respiratory tract symptoms and improves mood status. The findings of this study should be confirmed by double-blind trials with a larger number of participants.

## Full-text entities

- **Diseases:** runny (MESH:D000086722), nasal (MESH:D009668), nasal upper respiratory tract symptoms (MESH:D012141)

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11279517/full.md

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Source: https://tomesphere.com/paper/PMC11279517