Independent Concentration Manipulation Using Sidewall-Driven Micromixer
Toshio Takayama, Hayato Maki
TL;DR
A new micromixer design allows independent concentration control in each chamber for precise biochemical experiments.
Contribution
A sidewall-driven micromixer with individual actuators per chamber for independent mixing of different chemicals.
Findings
Independent mixing in each chamber was achieved using one actuator per chamber.
Different conditions were successfully created in each chamber using microbeads and colored water.
The mixer works for both particles and fluids, enabling versatile concentration manipulation.
Abstract
Lab-on-a-chip technology has been developed to streamline biochemical experiments by providing experimental environments in microscopic areas. Due to the difficulty of mixing chemicals in such small channels, various micromixers have been created. Our proposed sidewall-driven micromixer offers easy fabrication and precise control over mixing concentrations. In our previous study, we successfully generated concentration gradients by simultaneously mixing multiple chambers using a single actuator. However, it is not possible to mix different chemicals in each chamber. In this study, we developed a sidewall-driven micromixer that enables independent mixing in each chamber by installing one actuator per chamber. Experimental results showed that different conditions were achieved in each chamber using both microbead-mixture water and colored water. Thus, this mixer can be used to manipulate…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9
Figure 10
Figure 11
Figure 12
Figure 13
Figure 14Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMicrofluidic and Capillary Electrophoresis Applications · Microfluidic and Bio-sensing Technologies · Innovative Microfluidic and Catalytic Techniques Innovation