# Influence of Meteorological Parameters on the Prevalence of TEE Detected Left Atrial Appendage Thrombi

## TL;DR

This study found that certain weather conditions in spring and summer are linked to a higher occurrence of blood clots in the left atrial appendage.

## Contribution

The study identifies specific meteorological factors associated with increased prevalence of left atrial appendage thrombi.

## Key findings

- F-months with frequent thrombi diagnoses occurred mainly in spring, summer, February, and November.
- F-months showed higher temperature differences, lower humidity, longer sunshine, and higher wind speeds compared to N-months.
- Higher average and maximum temperatures were observed in F-months during the two-week period.

## Abstract

(1) Background: Meteorological factors seem to exert various effects on human health, influencing the occurrence of diseases such as thromboembolic events and strokes. Low atmospheric pressure in summer may be associated with an increased likelihood of ischemic stroke. The aim of this study was to investigate the potential impact of meteorological conditions on left atrial appendage (LAA) thrombus formation. (2) Methods: A total of 131 patients were included, diagnosed with a first instance of thrombus via 3D transesophageal echocardiography (TEE) between February 2009 and February 2019. Months with frequent thrombus diagnoses of at least 10 thrombi per month were categorized as frequent months (F-months), while months with fewer than 10 thrombus diagnoses per month were labelled as non-frequent months (N-months). The analysis focused on differences in meteorological parameters in two-week and four-week periods before the diagnosis. (3) Results: F-months were predominantly observed in spring and summer (April, May, June, and July), as well as in February and November. During F-months, a higher absolute temperature difference, lower relative humidity, longer daily sunshine duration, and greater wind speed maximum were observed in the two- and four-week periods rather than for N-months. In the two-week period, average temperatures, equivalent temperatures, and temperature maxima were also significantly higher during F-months than N-months. (4) Conclusion: Thrombi in the left atrial appendage are more prevalent during periods characterized by high absolute temperature differences, low relative humidity, and long daily sunshine duration.