# A Brief History of Cardiomyoplasty: Worth Another Look?

**Authors:** John A. Elefteriades

PMC · DOI: 10.31083/j.rcm2305159 · Reviews in Cardiovascular Medicine · 2022-04-28

## TL;DR

This paper reviews the history of cardiomyoplasty, a technique that used skeletal muscle to assist failing hearts, and suggests the concept might still have potential.

## Contribution

The paper re-evaluates the outdated cardiomyoplasty technique, proposing that its accessory pumping chambers could be reconsidered.

## Key findings

- Cardiomyoplasty was tested by wrapping skeletal muscle around failing hearts or creating accessory chambers.
- The cardiac wrap approach was found ineffective, leading to the decline of cardiomyoplasty.
- The concept of independent skeletal muscle ventricles may still hold promise for cardiac assistance.

## Abstract

This article reviews the concept and 
extensive experimentation done over two decades ago to convert and apply skeletal 
muscle for cardiac assistance—so called “cardiomyoplasty”. Skeletal muscle 
was either wrapped around a failing heart or fashioned into accessory cardiac 
pumping chambers. Although the era of cardiomyoplasty came to an end when the 
cardiac wraps were found ineffective, the concept of independent accessory 
skeletal muscle ventricles may be worth another look.

## Full-text entities

- **Diseases:** muscle (MESH:D019042), hypoventilation (MESH:D007040), diaphragm (MESH:D065630), ventricle (MESH:D002551), quadriplegia (MESH:D011782), heart  failure (MESH:D006333), Wrapping of the heart with skeletal muscle (MESH:C535850)
- **Chemicals:** Silicone elastomer (MESH:D012826)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11274049/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11274049/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC11274049/full.md

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Source: https://tomesphere.com/paper/PMC11274049