# Association between Physical Activity and the Risk of Mortality and Hospitalization in Older Korean Adults with Heart Failure

**Authors:** Ga-In Yu, Pil-Sung Yang, Moon-Hyun Kim, Moo-Nyun Jin, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung

PMC · DOI: 10.31083/j.rcm2305153 · Reviews in Cardiovascular Medicine · 2022-04-26

## TL;DR

This study shows that even light physical activity can reduce mortality risk in older Korean adults with heart failure.

## Contribution

The study identifies lower physical activity thresholds for mortality reduction in older Asian heart failure patients.

## Key findings

- Insufficiently active patients had a 18% lower mortality risk than inactive patients.
- Highly active patients had a 48% lower mortality risk compared to inactive patients.
- Benefits started at lower activity levels than WHO guidelines suggest.

## Abstract

Regular exercise improves the functional ability and 
quality of life of patients with heart failure (HF). However, studies on the 
results of intensity of exercise in the older population are scarce, especially 
in the Asian population.

A total of 8982 
older people (age ≥65 years) with HF were selected from the Korean 
National Health Insurance Service-Senior database (2005–2012). Participants were 
stratified according to the levels of physical activity per week as follows: (1) 
inactive group; (2) insufficiently active group: 1–499 metabolic equivalent task 
minutes (MET-min)/week; (3) active group: 500–999 MET-min/week; and (4) highly 
active group: ≥1000 MET-min/week. During a median follow-up 
period of 3.2 years, the incidence and risk of mortality were reduced in the 
insufficiently active (6.7 vs. 4.2 per 100 person-years, adjusted hazard ratio 
[HR], 0.82; 95% confidence interval [CI], 0.71–0.94; p < 0.001), 
active (3.8 per 100 person-years; HR, 0.81; 95% CI, 0.70–0.95; p = 
0.010), and highly active (2.4 per 100 person-years; HR, 0.52; 95% CI, 
0.41–0.67; p < 0.001) groups compared to inactive patients.

In older Asians with HF, increased physical activity 
reduced the risk of all-cause mortality. The mortality-reducing benefit started 
at a lower physical activity compared to the World Health Organization guideline 
(500–999 MET-min/week), and the risk decreased with more physical activity.

## Linked entities

- **Diseases:** heart failure (MONDO:0005252)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** HF (MESH:D006333), Mortality (MESH:D003643)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11273939/full.md

## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC11273939/full.md

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Source: https://tomesphere.com/paper/PMC11273939