# Multiple giant cutaneous metastasis and ileal intussusception from an unknown melanoma: A case report

## TL;DR

A 47-year-old man with an unknown melanoma developed large tumors and intestinal blockage, highlighting the rare and severe nature of melanoma in the gastrointestinal tract.

## Contribution

This case report presents a rare instance of melanoma with unknown origin causing multiple cutaneous metastases and ileal intussusception in an adult.

## Key findings

- The patient had multiple soft tissue tumors, with the largest in the left gluteal region.
- Melanoma was confirmed as the cause of ileo-ileal intussusception despite no identifiable primary skin lesion.
- Melanoma metastases in the gastrointestinal tract often present with severe symptoms and poor prognosis.

## Abstract

Intestinal intussusception is one of the most common causes of intestinal obstruction in children; however, the incidence in adults is lower, and is caused by tumors in the majority of cases. Melanoma of the gastrointestinal tract is relatively rare, with only a small number of cases having been reported. The majority of cases occur as metastasis from cutaneous primary lesions, and the small bowel is the most common location of melanoma metastases in the gastrointestinal tract. The present study describes the case of a 47-year-old male patient with multiple soft tissue tumors, the largest one located in the left gluteal region, measuring 14x15x20 cm. This tumor was biopsied and a differential diagnosis was made between clear cell sarcoma and melanoma. The patient was evaluated by a dermatologist, without identifying any skin lesions compatible with cutaneous melanomas and was admitted to the emergency room due to an ileo-ileal intussusception. The results of the pathological analysis confirmed the final diagnosis of melanoma. On the whole, these lesions are usually diagnosed with the onset of symptoms, presenting an ominous prognosis.