# Patent Ductus Arteriosus in Association With Agenesis of Corpus Callosum: Syndromic Links, Difficult Airway Challenges, and Pediatric Anesthesia Management

**Authors:** Urvi Sawant, Jayshree Sen, Dhawal Wadaskar

PMC · DOI: 10.7759/cureus.63177 · Cureus · 2024-06-26

## TL;DR

This paper discusses a rare case of a three-month-old infant with a heart defect and a brain development issue, focusing on anesthesia and medical management.

## Contribution

The paper presents a unique case linking patent ductus arteriosus with agenesis of the corpus callosum and addresses anesthesia challenges.

## Key findings

- The case highlights the syndromic association between patent ductus arteriosus and agenesis of corpus callosum.
- The paper emphasizes the challenges of managing a difficult airway in pediatric patients with these conditions.
- It provides insights into the anesthesia and procedural management for such rare cases.

## Abstract

Agenesis of corpus callosum (ACC) is a congenital absence of corpus callosum either completely or partially; without deficits in behavior or function during the first two years of life. Patent ductus arteriosus (PDA) is a congenital cardiac defect in which there is persistent contact between the pulmonary artery and the descending thoracic aorta due to failure of the normal physiologic closure of the fetal ductus. This article details a unique case of a three-month-old male infant who was initially diagnosed with PDA and later discovered to have corpus callosum agenesis. The child was posted on a PDA device for closure. Here, we will be discussing syndromic association, difficult airway, procedure-related factors, and pediatric anesthesia management of this rare case.

## Linked entities

- **Diseases:** Patent ductus arteriosus (MONDO:0011827), Agenesis of corpus callosum (MONDO:0009022)

## Full-text entities

- **Diseases:** congenital cardiac defect (MESH:D006331), PDA (MESH:D004374), ACC (MESH:D061085)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11273177/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11273177/full.md

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Source: https://tomesphere.com/paper/PMC11273177