# Kidney Stone Risk in Normocalcemic Hyperparathyroidism before and after Parathyroid Surgery

**Authors:** Jie Tang, Kamil Malshy, Gyan Pareek

PMC · DOI: 10.1155/2024/1252724 · Case Reports in Endocrinology · 2024-07-17

## TL;DR

This paper discusses a case where kidney stone risk remained high in a patient with normocalcemic hyperparathyroidism even after surgery.

## Contribution

The study presents a unique case showing that parathyroid surgery does not necessarily reduce kidney stone risk in normocalcemic hyperparathyroidism.

## Key findings

- Surgical resection of the parathyroid adenoma did not reduce kidney stone risk based on 24-hr urine studies.
- Kidney stone burden remained unchanged based on ultrasound findings after surgery.

## Abstract

The higher risk for kidney stone in patients with primary hyperparathyroidism is well-documented; stone risk in patients with normocalcemic primary hyperparathyroidism (NPHPT) remains unclear. We present a case of recurrent calcium kidney stones in a patient with severe idiopathic hypercalciuria and NPHPT. The surgical resection of the parathyroid adenoma failed to reduce kidney stone risk (based on the 24-hr urine study) and kidney stone burden (based on ultrasound). This unique case examines the impact of surgical resection of an ectopic parathyroid adenoma on stone risk in a patient with NPHPT and recurrent calcium kidney stones.

## Linked entities

- **Diseases:** primary hyperparathyroidism (MONDO:0010837)

## Full-text entities

- **Diseases:** parathyroid adenoma (MESH:D010282), idiopathic hypercalciuria (MESH:C562790), NPHPT (MESH:D049950), Kidney Stone (MESH:D007669), Hyperparathyroidism (MESH:D006961)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11272400/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11272400/full.md

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Source: https://tomesphere.com/paper/PMC11272400