# Abiotrophia defectiva Endocarditis: A Case Diagnosed Incidentally Due to Multi-organ Embolism

**Authors:** Fumitaka Suzuki, Masahiro Tsutsui, Hideki Isa, Shingo Kunioka, Hiroyuki Kamiya

PMC · DOI: 10.7759/cureus.63146 · Cureus · 2024-06-25

## TL;DR

A rare case of heart infection caused by Abiotrophia defectiva was successfully treated with surgery and antibiotics after multi-organ embolism.

## Contribution

This case highlights the successful multidimensional treatment of A. defectiva endocarditis despite its antibiotic resistance.

## Key findings

- A 53-year-old male with IgA nephropathy was diagnosed with A. defectiva endocarditis.
- Combination of surgical and antibiotic treatment led to a successful outcome.
- Emphasis is placed on early diagnosis and treatment to manage A. defectiva endocarditis.

## Abstract

Abiotrophia defectiva, often referred to as nutritionally variant streptococci, is generally a benign part of human microflora, primarily found in the oral cavity, digestive tract, and genitourinary system. However, it can have a significant role in infectious endocarditis (IE). We discuss a case involving a 53-year-old male who displayed serious signs indicative of IE. The individual, who had a history of IgA nephropathy, underwent successful surgical and antibiotic intervention. Given the challenge in treating A. defectiva due to its high antibiotic resistance and the tendency for embolic events and treatment failure, a multidimensional approach involving surgical intervention and specific antibiotic therapy resulted in a successful outcome. This case underlines the need for early identification, immediate treatment, and additional research to understand better and manage A. defectiva endocarditis.

## Linked entities

- **Diseases:** IgA nephropathy (MONDO:0005342)

## Full-text entities

- **Diseases:** A. defectiva endocarditis (MESH:D004696), IgA nephropathy (MESH:D005922), Multi-organ Embolism (MESH:D004617)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11272385/full.md

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Source: https://tomesphere.com/paper/PMC11272385