# Swyer-James Syndrome: A Rare Radiological Report of Two Cases Presenting in Adulthood

**Authors:** Khavin Kumar, Jeffrey S Joseph, Ramprasath Sathiamoorthy, Rajamani Anand, Einstien Arulraj

PMC · DOI: 10.7759/cureus.63123 · Cureus · 2024-06-25

## TL;DR

This paper reports two rare adult cases of Swyer-James syndrome, highlighting how radiological findings can help diagnose the condition even without a clear history of childhood infections.

## Contribution

The novelty lies in presenting two adult cases with atypical radiological features of Swyer-James syndrome.

## Key findings

- One patient showed unilateral hyperlucency on chest radiograph and a bilateral mosaic pattern on CT lung without childhood infection history.
- Another patient had unilateral hyperlucency with a history of childhood infection, confirming the diagnosis of SJS.
- Radiological findings proved crucial for accurate diagnosis when clinical history was inconclusive.

## Abstract

Swyer-James syndrome (SJS), also termed MacLeod syndrome, is an acquired secondary unilateral hyperlucency of the lung due to childhood lung infections. This disorder can be diagnosed in children; however if there are few or no symptoms, diagnosis can be missed and can then be detected later in adult life as an incidental finding. We present here the case reports of two patients, where one of them had a unique presentation of unilateral hyperlucency on a chest radiograph and a bilateral mosaic pattern on CT lung but with no history of childhood infections and another case with unilateral hyperlucency of the lung with the history of childhood infection were diagnosed as SJS. This article is important as it highlights the significant radiological finding in accurately diagnosing this condition, when the presenting complaint and past history are inconclusive, thereby guiding proper management.

## Full-text entities

- **Diseases:** lung (MESH:D008171), MacLeod syndrome (MESH:D019568), infection (MESH:D007239), lung infections (MESH:D012141)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11271755/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11271755/full.md

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Source: https://tomesphere.com/paper/PMC11271755