# Comparative Analysis of Ventilatory Responses during Stress Tests in Patients with Chronic Pain: Implications for Therapeutic Interventions

**Authors:** Patricio Barría, María Gaitán-Padilla, Daniel Gomez-Vargas, Gonzalo Cardenas Ampuero, Kay Gitterman, Bessie Cordova, Camilo A. R. Diaz, Flavio Roberti

PMC · DOI: 10.3390/jfmk9030122 · 2024-07-07

## TL;DR

This study compares how patients with fibromyalgia and other chronic pain conditions respond to exercise, showing that fibromyalgia patients have distinct ventilatory patterns that require tailored physical therapy.

## Contribution

The study identifies unique ventilatory responses in fibromyalgia patients during stress tests, suggesting the need for customized exercise interventions.

## Key findings

- Fibromyalgia patients had a reduced time for the aerobic threshold during exercise.
- They showed higher respiratory frequency at the anaerobic threshold compared to other chronic pain patients.
- Fibromyalgia patients had higher ventilatory coefficients during the test and recovery stages.

## Abstract

Understanding the differences in ventilatory responses during exercise between patients with fibromyalgia and those with other chronic pain disorders is crucial for developing effective therapeutic interventions, especially in exercise to identify the better physical therapy prescription. Both populations face unique challenges that impact their ability to engage in physical activity; yet, the underlying physiological responses can vary significantly. In this context, the methodology of this study entailed conducting a comparative analysis of the ventilatory response during exercise in patients with fibromyalgia and those with other chronic pain disorders. The experimental protocol included a total of 31 participants (n = 13 diagnosed with fibromyalgia and n = 18 diagnosed with other chronic pain conditions). All participants completed a stress test, where the ventilatory parameters were measured in three stages (i.e., resting, incremental exercise, and recovery). The results revealed significant differences (p<0.05) in ventilatory responses between both groups. Patients with fibromyalgia exhibited reduced time for the aerobic threshold and a higher respiratory frequency in the anaerobic threshold compared to those with other chronic pain disorders. Furthermore, fibromyalgia patients demonstrated higher values in the ventilatory coefficient during the test and in the recovery stage. In conclusion, these differences underscore the need for tailored exercise programs that specifically address the unique ventilatory challenges faced by fibromyalgia patients to improve their physical function and overall quality of life.

## Linked entities

- **Diseases:** fibromyalgia (MONDO:0005546)

## Full-text entities

- **Diseases:** fibromyalgia (MESH:D005356), Chronic Pain (MESH:D059350)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11270440/full.md

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Source: https://tomesphere.com/paper/PMC11270440