# Effect of COVID-19 Pandemic on Acute Coronary Syndrome Clinical Practice Patterns: Findings from a Multicenter Clinician Survey in China

**Authors:** Feng Hu, Minhua Zang, Lihui Zheng, Wensheng Chen, Jinrui Guo, Zhongpeng Du, Erpeng Liang, Lishui Shen, Xiaofeng Hu, Dezhong Zheng, Xuelian Xu, Gaifeng Hu, Aihua Li, Jianfeng Huang, Yan Yao, Jun Pu

PMC · DOI: 10.31083/j.rcm2311362 · 2022-10-25

## TL;DR

This study shows how the COVID-19 pandemic changed how doctors treat heart attacks and related conditions in China.

## Contribution

The study provides new insights into how the pandemic altered clinical decisions for acute coronary syndrome in China.

## Key findings

- Cardiologists reported fewer acute coronary syndrome patients during the pandemic.
- Invasive treatments like coronary interventions decreased, while drug treatments increased.
- Fibrinolytic therapy for heart attacks was used more often during the pandemic.

## Abstract

The 
coronavirus disease 2019 (COVID-19) pandemic has severely affected healthcare 
systems around the world. This study aimed to investigate the perceptions of 
cardiologists regarding how the COVID-19 pandemic has affected the clinical 
practice patterns for acute coronary syndrome (ACS).

A 
multicenter clinician survey was sent to 300 cardiologists working in 22 
provinces in China. The survey collected demographic information and inquired 
about their perceptions of how the COVID-19 pandemic has affected ACS clinical 
practice patterns.

The survey was completed by 211 (70.3%) 
cardiologists, 82.5% of whom were employed in tertiary hospitals, and 52.1% 
reported more than 10 years of clinical cardiology practice. Most respondents 
observed a reduction in ACS inpatients and outpatients in their hospitals during 
the pandemic. Only 29.9% of the respondents had access to a dedicated catheter 
room for the treatment of COVID-19-positive ACS patients. Most respondents stated 
that the COVID-19 pandemic had varying degrees of effect on the treatment of 
acute ST-segment elevation myocardial infarction (STEMI), acute non-ST-segment 
elevation myocardial infarction (NSTEMI), and unstable angina. Compared with the 
assumed non-pandemic period, in the designed clinical questions, the selection of 
coronary interventional therapy for STEMI, NSTEMI, and unstable angina during the 
COVID-19 pandemic was significantly decreased (all p < 0.05), and the 
selection of pharmacotherapy was increased (all p < 0.05). The 
selection of fibrinolytic therapy for STEMI during the pandemic was higher than 
in the assumed non-pandemic period (p < 0.05).

The COVID-19 pandemic has profoundly affected ACS 
clinical practice patterns. The use of invasive therapies significantly decreased 
during the pandemic period, whereas pharmacotherapy was more often prescribed by 
the cardiologists.

## Linked entities

- **Diseases:** coronavirus disease 2019 (MONDO:0100096), acute coronary syndrome (MONDO:0005542), acute ST-segment elevation myocardial infarction (MONDO:0041656), unstable angina (MONDO:0006805)

## Full-text entities

- **Diseases:** Pandemic (MESH:D000086382), unstable angina (MESH:D000789), NSTEMI (MESH:D000072657), ACS (MESH:D054058), myocardial infarction (MESH:D009203)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11269060/full.md

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Source: https://tomesphere.com/paper/PMC11269060