A Rare Case of Renal Angiomyolipoma and Polycystic Kidney Disease in a Patient with Tuberous Sclerosis

TL;DR

A 32-year-old woman with a rare combination of kidney tumor and cyst disease had surgery to remove the tumor.

Contribution

Reports a rare case of renal AML co-occurring with polycystic kidney disease in a tuberous sclerosis patient.

Findings

A 32-year-old female presented with a large renal AML confirmed via histopathology.

The patient had bilateral flank pain and a palpable mass, leading to left radical nephrectomy.

This case highlights the uncommon coexistence of AML and polycystic kidney disease.

Abstract

Renal angiomyolipoma (AML) is a rare benign tumor that follows an autosomal dominant inheritance pattern. Its association with polycystic kidney disease is uncommon, with only a handful of cases documented in the literature. The growth of lesions to a significant size may lead to life-threatening complications. We report a case of a 32-year-old female who presented with a palpable mass and bilateral flank pain. Following clinical assessment and CT examination, the patient underwent a left radical nephrectomy. The resected mass measured 9.3 x 8.2 x 7.5 cm, and the subsequent histopathological examination confirmed the diagnosis as renal AML.

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