# Oculoplastic Conditions in Covid-19 Patients: Case Series and Literature Review

**Authors:** Camille Yvon, Bhupendra Patel, John Ng, Marcus T Altman, Raman Malhotra

PMC · DOI: 10.18502/jovr.v19i2.10908 · Journal of Ophthalmic & Vision Research · 2024-06-21

## TL;DR

This study reports oculoplastic conditions in male COVID-19 patients, showing inflammation and swelling that improved with steroids.

## Contribution

The paper presents a novel case series linking oculoplastic conditions to COVID-19 with a focus on male patients.

## Key findings

- Four male patients developed eyelid, orbital, or lacrimal gland issues within four weeks of testing positive for COVID-19.
- Three patients fully recovered, and one partially recovered within an average of 2.7 weeks, with steroids aiding recovery.
- Adnexal manifestations include self-limiting orbital inflammation and eyelid lymphedema.

## Abstract

To investigate oculoplastic conditions in patients diagnosed with coronavirus disease 2019 (COVID-19) seen at ophthalmology departments of three tertiary referral centers in the United Kingdom and the United States, and review of the literature.

Retrospective multicenter case series studied over 18 months.

A total of four patients developed eyelid, orbital, or lacrimal gland pathology within four weeks of testing positive for COVID-19. All were male, and the mean age at presentation was 49 (range, 31–58 years). Suspected diagnoses included anterior idiopathic orbital inflammation, facial angioedema, dacryoadenitis, and anophthalmic socket inflammation. Three patients recovered fully and one patient recovered partially (mean 2.7 weeks) from ocular manifestations with steroids hastening recovery.

Adnexal manifestations of COVID-19 include self-limiting orbital inflammation and eyelid lymphedema.

## Linked entities

- **Diseases:** coronavirus disease 2019 (MONDO:0100096), dacryoadenitis (MONDO:0004804)

## Full-text entities

- **Diseases:** eyelid lymphedema (MESH:D005141), Oculoplastic Conditions (MESH:D020763), anophthalmic socket inflammation (MESH:D007249), dacryoadenitis (MESH:D003607), COVID-19 (MESH:D000086382), facial angioedema (MESH:D000799)
- **Chemicals:** steroids (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11267130/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11267130/full.md

## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC11267130/full.md

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Source: https://tomesphere.com/paper/PMC11267130