# Combined Brilliant and Trypan Blue As Vital Dyes for Chromovitrectomy

## TL;DR

A new dye combination improves visibility during eye surgeries by effectively staining retinal membranes.

## Contribution

A 1:1 mixture of Brilliant Blue and Trypan Blue provides better staining contrast for retinal surgeries.

## Key findings

- The dye combination sinks quickly to the posterior pole with minimal diffusion.
- It effectively stains the internal limiting membrane and epiretinal membrane during surgeries.
- The mixture improves contrast for surgeries on macular holes and related conditions.

## Abstract

Brilliant blue 0.05% and trypan blue 0.1% were mixed in a proportion of 1:1 in a 1-mL syringe. This combination produced a waterfall effect with the fast sinking of the dye to the posterior pole and little diffusion through the vitreous cavity. Therefore, it can effectively stain the internal limiting membrane and the epiretinal membrane with a good contrast during surgeries for a macular hole, myopic foveoschisis, and macular pucker.