# 18F-FDG whole-body PET/CT for the evaluation of suspected native valve infective endocarditis

**Authors:** Shihan Chen, Noah Ben-Ezra, Stephan Probst, Gad Abikhzer

PMC · DOI: 10.1186/s41824-024-00207-7 · 2024-07-22

## TL;DR

This paper discusses how a PET/CT scan can help diagnose heart and body infections in a patient with a suspected heart valve infection.

## Contribution

The paper highlights the use of whole-body FDG-PET/CT in diagnosing native valve infective endocarditis and detecting related complications.

## Key findings

- PET/CT revealed left foot osteomyelitis in a patient with persistent MRSA bacteremia.
- Whole-body PET/CT diagnosed native mitral valve infective endocarditis and septic pulmonary embolism.
- FDG-PET/CT aids in detecting intra-cardiac infections and their sources.

## Abstract

18F-FDG-PET/CT is indicated in the workup of patients with suspected infective endocarditis to detect intra-cardiac and disseminated infections, as well as its source. We present the case of a 66-year-old female patient known for recurrent diabetic foot infection, with equivocal TTE results and persistent MRSA bacteremia despite medical management. PET/CT revealed evidence of left foot osteomyelitis. Whole body PET/CT diagnosed native mitral valve infective endocarditis (IE) and right lower lobe segmental pulmonary artery uptake, consistent with septic pulmonary embolism (PE).

Whole-body FDG-PET/CT can contribute to the diagnosis, source assessment, and embolic detection of NVE.

## Linked entities

- **Chemicals:** 18F-FDG (PubChem CID 68614)
- **Diseases:** infective endocarditis (MONDO:0000565), osteomyelitis (MONDO:0005246)

## Full-text entities

- **Diseases:** PE (MESH:D011655), mitral valve infective endocarditis (MESH:D008944), infections (MESH:D007239), osteomyelitis (MESH:D010019), bacteremia (MESH:D016470), diabetic foot infection (MESH:D017719), IE (MESH:D004696)
- **Chemicals:** 18F-FDG (MESH:D019788)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11265061/full.md

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Source: https://tomesphere.com/paper/PMC11265061