# X marks the spot: catheter aspiration using the Inari FlowTriever device to debulk defibrillator lead vegetations prior to transvenous lead extraction—a case report

**Authors:** James Clark, Abbas Zaidi, Peter O’Callaghan, Ulrich von Oppell, Andrew S P Sharp

PMC · DOI: 10.1093/ehjcr/ytae332 · 2024-07-11

## TL;DR

A new method using the Inari FlowTriever device safely removes large vegetations from a defibrillator lead before extraction, avoiding open heart surgery.

## Contribution

Demonstrates a novel single-access aspiration technique using the Inari FlowTriever for lead debulking without extracorporeal bypass.

## Key findings

- The Inari FlowTriever successfully debulked large vegetations from a defibrillator lead.
- The technique used fluoroscopy and transoesophageal echocardiogram guidance for localization.
- The method required only a single venous puncture and avoided extracorporeal bypass.

## Abstract

When cardiac implantable electronic device infection occurs, standard therapy is usually total system extraction. Transvenous lead extraction is preferable to open heart surgical extraction, unless contraindicated because of the presence of very large vegetations on the intravenous leads according to the European Society of Cardiology guidelines. Extraction of transvenous leads with vegetations risks distal embolism resulting in obstruction and/or infection in the pulmonary arteries. Catheter aspiration of vegetations or thrombi has been performed prior to transvenous lead extraction using a partial veno-venous extracorporeal bypass circuit. We report the use of a single-access aspiration system using the Inari FlowTriever 24 French system to debulk a defibrillator lead before percutaneous extraction.

A 79-year-old male presented with fever 18 years after his first implantable cardioverter defibrillator implant and 9 years after his most recent pulse generator change. Two large vegetations were identified on his transvenous defibrillator lead on the atrial aspect, near the tricuspid annulus, which were aspirated using the Inari Medical 24Fr FlowTriever aspiration catheter. We describe anatomical considerations during the approach and a technique to localize the vegetations based on a combination of fluoroscopy and transoesophageal echocardiogram guidance.

This case demonstrates the safe and effective use of the Inari Medical 24Fr FlowTriever aspiration catheter in debulking a defibrillator lead before transvenous lead extraction. This method uses a single venous puncture and is not dependent on extracorporeal bypass. Apart from reducing complexity, this technique may be advantageous in patients where anticoagulation needs to be minimised.

## Full-text entities

- **Diseases:** infection (MESH:D007239), fever (MESH:D005334), embolism (MESH:D004617), cardiac implantable electronic device infection (MESH:D009471)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11263866/full.md

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Source: https://tomesphere.com/paper/PMC11263866