Recurrent Cervical Lymphadenitis Responding to Antibiotics Turned Out to Be Lymphoma on Biopsy: A Case Report

TL;DR

A patient with recurring neck lymph node swelling initially improved with antibiotics but was later diagnosed with lymphoma after a biopsy.

Contribution

Highlights the importance of biopsy in persistent lymphadenitis cases to detect underlying malignancies.

Findings

Recurrent cervical lymphadenitis responding to antibiotics can still be a sign of lymphoma.

Biopsy is crucial for accurate diagnosis in persistent lymphadenopathy cases.

Prompt evaluation prevents delayed diagnosis of malignancies.

Abstract

Recurrent cervical lymphadenitis is a common clinical presentation often managed with empiric antibiotic therapy. However, despite antibiotic treatment, persistent lymphadenopathy warrants consideration of alternative etiologies, including malignancy. We present the case of a 71-year-old female with recurrent cervical lymphadenitis that initially responded to antibiotics but was ultimately diagnosed as lymphoma upon biopsy. Despite conservative management, the patient's symptoms persisted, prompting surgical excision of the lymph node. Histopathological examination confirmed the lymphoma diagnosis, highlighting the importance of considering malignancy in cases of persistent lymphadenitis. This case underscores the significance of prompt evaluation, including biopsy, to ensure timely diagnosis and appropriate management in patients with recurrent cervical lymphadenitis.

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