# An Interesting Case of Wolf-Parkinson-White Syndrome in a Young Patient With Sensorineural Deafness

**Authors:** Zahid Khan, Ayub Khan

PMC · DOI: 10.7759/cureus.62928 · 2024-06-22

## TL;DR

A 17-year-old man with sensorineural deafness and a family history of it was diagnosed with WPW syndrome and successfully treated with ablation.

## Contribution

This case report highlights a rare association of WPW syndrome with sensorineural deafness and a family history of the condition.

## Key findings

- The patient had WPW syndrome type A confirmed by ECG findings including a short PR interval and delta waves.
- The patient had sensorineural deafness since childhood with a family history of the same condition.
- Ablation successfully resolved WPW syndrome signs and resulted in post-ablation ECG features like peak T waves.

## Abstract

Wolff-Parkinson-White (WPW) syndrome is a condition associated with tachycardia due to accessory pathways in the heart, and it is one of the most common causes of tachycardia in infants and children. WPW may also be associated with mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS syndrome) or LEOPARD syndrome (LS). We report a case of pre-excitation WPW syndrome in a 17-year-old man who was brought to the hospital by ambulance following the collapse. WPW syndrome type A was diagnosed from precordial leads. Electrocardiography (ECG) revealed a short PR interval, delta waves, and positive waves with dominant R in all pericardial leads. Blood test results showed an isolated elevated ALT level. Subsequent echocardiography was unremarkable, with an ejection fraction of 55%, apart from septal and inferior wall dyssynchrony. With regard to the past medical history, he had sensorineural deafness (SND) since childhood and had a family history of SND. Consequently, the patient was transferred to the cardiac electrophysiology department at another hospital after consultation and underwent ablation. A successful post-ablation electrocardiogram revealed the resolution of the WPW syndrome signs and post-ablation features, such as peak T waves.

## Linked entities

- **Diseases:** Wolff-Parkinson-White syndrome (MONDO:0008685), MELAS syndrome (MONDO:0010789), LEOPARD syndrome (MONDO:0007893), sensorineural deafness (MONDO:0010576)

## Full-text entities

- **Diseases:** WPW syndrome (MESH:D014927), SND (MESH:D006319), tachycardia (MESH:D013610), mitochondrial encephalomyopathy (MESH:D017237), lactic acidosis (MESH:D000140), MELAS syndrome (MESH:D017241), LEOPARD syndrome (MESH:D044542)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11262883/full.md

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Source: https://tomesphere.com/paper/PMC11262883