# Research Advances in Targeted Therapy for Heart Failure

**Authors:** Liu Miao, Yan-Li Liu

PMC · DOI: 10.31083/j.rcm2410276 · 2023-10-07

## TL;DR

This paper discusses the importance of exploring new treatment targets for heart failure, a major health issue in China.

## Contribution

The paper emphasizes the need to investigate potential pathogenic mechanisms and identify new therapeutic targets for heart failure.

## Key findings

- Heart failure prevalence and mortality are increasing in China.
- Current treatments for heart failure are not satisfactory.
- Identifying new therapeutic targets is crucial for improving outcomes.

## Abstract

Cardiovascular disease is one of the major diseases threatening the health of 
Chinese residents, and the death rate has long been the highest on the disease 
spectrum in China. With the progress of population aging, the prevalence and 
mortality of cardiovascular diseases remain on the rise, and the current 
treatment effect on and prognosis of heart failure (HF) are not satisfactory. It 
is particularly important to explore the potential pathogenic mechanisms of HF 
and identify new therapeutic targets.

## Linked entities

- **Diseases:** heart failure (MONDO:0005252), cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** HF (MESH:D006333), death (MESH:D003643), Cardiovascular disease (MESH:D002318)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11262442/full.md

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Source: https://tomesphere.com/paper/PMC11262442