Coronavirus Disease 2019 and Takotsubo Syndrome
Ling Zhou, Zijun Chen, Riyue Jiang, Yimin Hu, Bin Zhu, Chun Yang, Ling Yang, Cunming Liu

TL;DR
This paper reviews the link between coronavirus disease 2019 (COVID-19) and Takotsubo syndrome, a heart condition, focusing on how they are connected and managed.
Contribution
The paper provides a comprehensive overview of TTS in the context of COVID-19, summarizing current understanding and treatment strategies.
Findings
Takotsubo syndrome is increasingly diagnosed in patients with COVID-19.
ACE2 receptors in the lungs and heart may play a role in the pathophysiology of TTS in these patients.
There is a lack of randomized studies on TTS related to COVID-19, leaving its mechanisms unclear.
Abstract
The novel coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global public health emergency. As the number of confirmed cases increases, cardiovascular complications, such as myocardial injury and cardiac dysfunction, are evidenced. Takotsubo syndrome (TTS), which is common in the intensive care unit, is diagnosed among COVID-19 patients. There have been 68 more cases reports with over 119 patients since a COVID-19 patient with TTS was first reported on April 14, 2020. Angiotensin-converting enzyme 2 (ACE2), which is widely expressed in the lungs and heart, is the virus receptor. Nevertheless, randomized studies on COVID-19 related TTS are lacking, and the pathogenesis and pathophysiology are still unclear. Therefore, this review provides an overview of the potential pathogenesis, pathophysiology,…
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Taxonomy
TopicsTakotsubo Cardiomyopathy and Associated Phenomena · Long-Term Effects of COVID-19 · Cardiac Health and Mental Health
