# Severe Acute Respiratory Distress in a Child with Hypereosinophilic Syndrome: A Case Report

**Authors:** Bipesh Kumar Shah, Shankar Prasad Yadav, Dheeraj Nagpal, Naveen Pokhrel, Samiksha Lamichhane

PMC · DOI: 10.31729/jnma.8579 · JNMA: Journal of the Nepal Medical Association · 2024-05-31

## TL;DR

A child with a rare condition causing high eosinophils and severe lung issues was treated with steroids and anthelmintics.

## Contribution

The case emphasizes the importance of early diagnosis and treatment of hypereosinophilic syndrome in children.

## Key findings

- The patient showed respiratory distress with pulmonary infiltrates and effusion.
- Treatment with corticosteroids and Diethylcarbamazine improved the condition.
- Multiorgan involvement was observed, including heart and liver.

## Abstract

Hypereosinophilic syndrome with respiratory distress and multiorgan involvement is not so common in children. It is essential to identify this entity based on clinical, laboratory, and imaging features. Corticosteroids should be instituted at the earliest to stabilize the patient and prevent organ damage. Tropical infections are a common secondary cause in children warranting the administration of Diethylcarbamazine. We present a case of an adolescent male in respiratory distress with marked eosinophilia and organs involving the lungs (pulmonary infiltrates with effusion), heart (pericardial effusion), and abdomen (ascites with infiltrates in the liver) which was managed with steroids and anthelmintics. The case highlights the importance of identifying patients with Hypereosinophilic syndrome in pursuing thorough evaluation and commencing therapy.

## Linked entities

- **Chemicals:** Diethylcarbamazine (PubChem CID 3052)
- **Diseases:** Hypereosinophilic syndrome (MONDO:0015691)

## Full-text entities

- **Diseases:** Acute (MESH:D000208), Severe (MESH:D045169), pulmonary infiltrates (MESH:D017254), Tropical infections (MESH:D007239), organ damage (MESH:D000092124), Hypereosinophilic Syndrome (MESH:D017681), Respiratory Distress (MESH:D012128), pericardial effusion (MESH:D010490), eosinophilia (MESH:D004802), ascites (MESH:D001201), effusion (MESH:D000080324), infiltrates in the liver (MESH:D017093)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11261552/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC11261552/full.md

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Source: https://tomesphere.com/paper/PMC11261552