# Harnessing mRNA to unleash endolysins: A new frontier in antibacterial therapy

**Authors:** Daniel C. Nelson, Urmil M. Dave, Norberto Gonzalez-Juarbe

PMC · DOI: 10.1016/j.omtn.2024.102249 · Molecular Therapy. Nucleic Acids · 2024-06-26

## Full-text entities

- **Genes:** LYZ (lysozyme) [NCBI Gene 4069] {aka AMYLD5, LYZF1, LZM}, HBA2 (hemoglobin subunit alpha 2) [NCBI Gene 3040] {aka ECYT7, HBA-T2, HBH}
- **Diseases:** pneumococcal pneumonia (MESH:D011018), bacterial (MESH:D001424), inflammation (MESH:D007249), bacterial colonization (MESH:D015179), Fabry disease (MESH:D000795), atopic dermatitis (MESH:D003876), cancer (MESH:D009369), infection (MESH:D007239), infectious diseases (MESH:D003141), COVID-19 (MESH:D000086382), pharyngitis (MESH:D010612), bacterial vaginosis (MESH:D016585), pneumococcal disease (MESH:D011008), urinary tract infection (MESH:D014552), osteomyelitis (MESH:D010019), eczema (MESH:D004485), hemophilia (MESH:D006467), streptococcal (MESH:D013290), cystic fibrosis (MESH:D003550)
- **Chemicals:** uridine (MESH:D014529), N1-methylpseudouridine (MESH:C013608), methicillin (MESH:D008712), poly(A) (MESH:D011061)
- **Species:** Gardnerella (genus) [taxon 2701], Pseudomonas aeruginosa (species) [taxon 287], Bacteriophage sp. (species) [taxon 38018], Staphylococcus aureus (species) [taxon 1280], Streptococcus sp. 'group B' (species) [taxon 1319], Streptococcus pneumoniae (species) [taxon 1313], Homo sapiens (human, species) [taxon 9606]

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## References

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Source: https://tomesphere.com/paper/PMC11260834