# Dysarthria as a Presenting Symptom With Rapidly Progressive Imaging Features in Sporadic Creutzfeldt-Jakob Disease: A Case Report

## TL;DR

This case report describes a rare and rapidly progressing brain disease that initially showed speech difficulties and unusual MRI findings.

## Contribution

The paper presents a unique case of sCJD with atypical early symptoms and rapid imaging changes.

## Key findings

- The patient showed dysarthria as the first symptom of sCJD.
- MRI scans revealed rapid progression of neurological damage.
- The case highlights the variability in sCJD clinical presentation.

## Abstract

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare and fatal neurodegenerative disorder belonging to a group of diseases known as prion disease. Characterized by the formation of abnormal prion proteins in the brain, these conditions lead to tissue damage and vacuolation, giving the brain a sponge-like appearance. sCJD represents the most prevalent form of CJD, accounting for roughly 85% of all CJD cases. We report a case with unusual clinical manifestations. The patient experienced progressive neurological symptoms and MRI progression.