# Cerebral Venous Sinus Thrombosis (CVST): A Clinically Significant Neurological Condition

**Authors:** Utkarsh Gaur, Charuta Gadkari, Aditya Pundkar

PMC · DOI: 10.7759/cureus.62700 · 2024-06-19

## TL;DR

This case study highlights cerebral venous sinus thrombosis (CVST), a rare neurological condition, and emphasizes the importance of early diagnosis and treatment for better patient outcomes.

## Contribution

The paper presents a unique case of CVST with unusual anatomical findings and underscores its diagnostic significance in neurological disorders.

## Key findings

- A 45-year-old man with CVST showed absent venous structures on MRV despite normal MRI results.
- The patient's symptoms improved with anticoagulant therapy, highlighting the effectiveness of treatment.
- The case underscores the need for multidisciplinary approaches in diagnosing and managing CVST.

## Abstract

Cerebral venous sinus thrombosis (CVST), a rare but deadly disorder, causes papilledema as well as a number of frequent clinical symptoms, including excruciating headaches, focal seizures, and paralysis on one or both sides of the body.

In this intriguing case study, we present the clinical narrative of a 45-year-old man who sought medical attention due to severe headaches persisting for two days. Concurrently, he experienced an abrupt onset of tingling and numbness in his left upper arm. Remarkably, magnetic resonance venography (MRV) revealed an absence of the sigmoid sinus, left transverse sinus, left jugular vein, and superior sagittal sinus, adding complexity to the diagnostic puzzle. Despite this anomaly, conventional brain MRI findings appeared normal. The patient reported a significant reduction in headache intensity following treatment, which included a year-long course of anticoagulant therapy. Subsequently, he gradually regained his health, underscoring the importance of multidisciplinary approaches in managing such challenging cases.

This example emphasizes the significance of considering CVST while developing a differential diagnosis of various neurological disorders. Given the vast spectrum of clinical symptoms associated with CVST, it should be taken into account as a potential causative factor in a number of neurological illnesses, in order for patients to experience the best outcomes, quick diagnosis, and quality care.

## Linked entities

- **Diseases:** papilledema (MONDO:0006879)

## Full-text entities

- **Diseases:** seizures (MESH:D012640), Neurological Condition (MESH:D019636), tingling and numbness (MESH:D006987), headache (MESH:D006261), papilledema (MESH:D010211), paralysis (MESH:D010243), neurological disorders (MESH:D009461), CVST (MESH:D012851)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11259092/full.md

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Source: https://tomesphere.com/paper/PMC11259092