A Case Report of Myxedema Coma in the Setting of Normal Thyroid Stimulating Hormone
Klynt Bally, Rhonda-Kaye Trusty, Kamrun Naher

TL;DR
This case report describes a rare instance of myxedema coma with normal TSH levels, highlighting the importance of clinical diagnosis in hypothyroidism.
Contribution
The novelty lies in presenting a myxedema coma case with normal TSH, challenging typical diagnostic criteria.
Findings
Myxedema coma can occur with normal thyroid stimulating hormone (TSH) levels.
Free thyroxine (FT4) was only mildly decreased in this severe case.
Clinical diagnosis is crucial even when hormone levels appear normal.
Abstract
Myxedema coma (MC) is a potentially fatal complication of hypothyroidism, with a high mortality rate. It is a clinically diagnosed condition, where the symptoms are related to decreased metabolic effects due to low active thyroid hormones. This case report highlights a severe case of MC, despite the thyroid stimulating hormone (TSH) being normal and the free thyroxine (FT4) being very mildly decreased.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsThyroid Disorders and Treatments · Thyroid Cancer Diagnosis and Treatment · Pituitary Gland Disorders and Treatments
