# Isolated Cardiac Sarcoidosis Presenting as High-Degree Atrioventricular Block

**Authors:** Ryian Owusu, Hazem Alakhras, Kateryna Strubchevska, Daniel G Walsh

PMC · DOI: 10.7759/cureus.62685 · 2024-06-19

## TL;DR

A 79-year-old man was diagnosed with isolated cardiac sarcoidosis after presenting with a severe heart block and no other typical symptoms.

## Contribution

This case highlights the challenges in diagnosing isolated cardiac sarcoidosis and the use of advanced imaging for confirmation.

## Key findings

- The patient's high-degree atrioventricular block was attributed to isolated cardiac sarcoidosis after ruling out other causes.
- Advanced cardiac imaging confirmed sarcoidosis without evidence of pulmonary involvement.
- The patient was treated with a biventricular ICD and corticosteroids.

## Abstract

Isolated cardiac sarcoidosis is a rare phenomenon of systemic sarcoidosis, with presentation ranging from asymptomatic to sudden cardiac death. Controversy exists on diagnostic and therapeutic options, creating an ongoing challenge for clinicians in providing patient care. A 79-year-old male presented status post looposcopy and interval ureteral stent replacement with sinus bradycardia and high-degree atrioventricular block. A comprehensive examination was performed that conclusively ruled out common etiologies of atrioventricular block, including coronary artery disease, electrolyte abnormalities, and medications. This prompted an investigation using advanced cardiac imaging modalities that demonstrated cardiac sarcoidosis. Computed tomography of the chest was negative for lymphadenopathy or infiltrates indicative of pulmonary involvement. The lack of extracardiac manifestations, in combination with imaging findings, led to a probable diagnosis of isolated cardiac sarcoidosis. The patient underwent biventricular implantable cardioverter defibrillator placement and was started on oral corticosteroids.

## Linked entities

- **Diseases:** cardiac sarcoidosis (MONDO:0001707), atrioventricular block (MONDO:0000465), coronary artery disease (MONDO:0005010)

## Full-text entities

- **Diseases:** lymphadenopathy (MESH:D008206), Cardiac Sarcoidosis (MESH:D012507), pulmonary involvement (MESH:C566343), infiltrates (MESH:D017254), coronary artery disease (MESH:D003324), bradycardia (MESH:D001919), electrolyte abnormalities (MESH:D014883), sudden cardiac death (MESH:D016757), Atrioventricular Block (MESH:D054537)
- **Chemicals:** ureteral stent (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11258927/full.md

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Source: https://tomesphere.com/paper/PMC11258927