# A cohort study of the effects of social support on cerebral cardiovascular disease in subjects with metabolic syndrome

**Authors:** Sung-Kyung Kim, Yong Whi Jeong, Dae Ryong Kang, Jang Young Kim, Hunju Lee, Sang-baek Koh

PMC · DOI: 10.1371/journal.pone.0305637 · 2024-07-18

## TL;DR

This study finds that low social support increases the risk of cerebral cardiovascular disease in people with metabolic syndrome.

## Contribution

It is the first study to show that social support is a risk factor for cerebral cardiovascular disease in metabolic syndrome patients.

## Key findings

- Low social support was associated with a 1.97 times higher risk of cerebral cardiovascular events in metabolic syndrome patients.
- The study highlights the importance of incorporating social support into risk assessments for metabolic syndrome and cardiovascular disease.

## Abstract

Previous studies have extensively examined the relationship between social support and various health outcomes. However, little is known about the distinct longitudinal associations between perceived social support and the development of cardiovascular events in patients with metabolic syndrome. In this cohort study, we investigated whether the levels of perceived social support in patients with metabolic syndrome were associated with an increased risk of cerebrovascular and cardiovascular events.

The level of social support was assessed using the Medical Outcomes Study-Social Support Survey (MOS-SSS) in 2,721 individuals living in Wonju and Pyeongchang, South Korea. The presence of metabolic syndrome was determined by physical measurements and blood tests, and the occurrence of cerebral cardiovascular disease in relation to the presence of metabolic syndrome and the level of social support was analyzed using Cox proportional-hazards models.

The median follow-up period was 2,345 days (2,192–2,618). Overall, in the group with metabolic syndrome and low social support, low social support was associated with an increased risk of later cerebral cardiovascular events; in this group, the hazard ratio after adjusting for confounding variables was 1.97 times (95% confidence interval, 1.01–3.85) higher than that in the group without metabolic syndrome and low social support.

This study shows, for the first time, that the level of social support is a risk factor for preventing cerebral cardiovascular disease in patients with metabolic syndrome and suggests that social support status should be incorporated into multifactorial risk assessment and intervention procedures to prevent metabolic syndrome and cerebral cardiovascular disease.

## Linked entities

- **Diseases:** metabolic syndrome (MONDO:0000816), cerebrovascular disease (MONDO:0011057), cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** cardiovascular (MESH:D002318), cerebral (MESH:D002547), metabolic syndrome (MESH:D024821)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11257245/full.md

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Source: https://tomesphere.com/paper/PMC11257245