# Cooccurrence of Myasthenia Gravis and Epilepsy: A Case Report

**Authors:** Intissar Barbouch, Bouchra Ennar, Kaoutar Chhita, Yassine Mebrouk

PMC · DOI: 10.7759/cureus.62601 · 2024-06-18

## TL;DR

A 34-year-old woman with epilepsy developed myasthenia gravis, highlighting the rare but important connection between these two neurological conditions.

## Contribution

This case report highlights the rare co-occurrence of myasthenia gravis and epilepsy, emphasizing treatment considerations.

## Key findings

- A 34-year-old woman with epilepsy developed myasthenia gravis at age 33.
- Antiepileptic drugs may worsen myasthenia gravis symptoms.
- The co-occurrence of these conditions is rare and requires careful treatment selection.

## Abstract

Myasthenia gravis (MG) is an autoimmune disease characterized by weakness and rapid fatigue of the voluntary muscles. Epilepsy is a neurological disorder marked by recurrent, unprovoked seizures. We present a case of a 34-year-old woman with idiopathic generalized epilepsy who developed MG at 33. While the relationship between MG and epilepsy remains unclear, it is known that antiepileptic drugs can exacerbate MG. The rarity of this association suggests a need for cautious selection of antiepileptic treatments to avoid worsening either condition.

## Linked entities

- **Diseases:** myasthenia gravis (MONDO:0009688), epilepsy (MONDO:0005027)

## Full-text entities

- **Diseases:** Epilepsy (MESH:D004827), seizures (MESH:D012640), autoimmune disease (MESH:D001327), idiopathic generalized epilepsy (MESH:C562694), weakness (MESH:D018908), muscles (MESH:D019042), fatigue of the (MESH:D005221), MG (MESH:D009157), neurological disorder (MESH:D009461)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11256970/full.md

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Source: https://tomesphere.com/paper/PMC11256970