# Insidious Synovial Sarcoma of Bone in a Patient with Rheumatoid Arthritis

**Authors:** Juan Carlos Reyes Villarreal, Luis Francisco Pineda-Galindo, Olga Vera-Lastra, Elizabeth Natalia Quispe-Susara, Alberto Ordinola Navarro

PMC · DOI: 10.1055/s-0041-1739172 · Revista Brasileira de Ortopedia · 2021-11-11

## TL;DR

A rare bone tumor was misdiagnosed as rheumatoid arthritis, leading to a fatal outcome due to delayed detection and complications.

## Contribution

Highlights diagnostic challenges of synovial sarcoma when it originates in bone and lacks palpable mass.

## Key findings

- Synovial sarcoma can present as hip pain without a palpable mass, leading to misdiagnosis.
- Delayed diagnosis due to symptom overlap with rheumatoid arthritis can result in fatal outcomes.
- Small or deep tumors are particularly challenging to detect and diagnose.

## Abstract

Synovial sarcoma is a rare malignity of mesenchymal origin; the diagnostic approach usually begins by documenting a soft tissue tumor; however, it results in a challenging diagnosis when it is more profound, of small size, or primary from the bone.

The present report describes a patient who presented insidious onset hip pain attributed to rheumatoid arthritis, with a fatal outcome due to baseline disease and surgery complications.

The underestimation of hip pain, mainly when there is no palpable mass, may delay the diagnosis.

Sarcoma sinovial é uma rara malignidade de origem mesenquimal; a abordagem diagnóstica geralmente começa documentando um tumor de tecido mole; no entanto, resulta em um diagnóstico desafiador quando é mais profundo, de pequeno porte ou primário do osso.

O presente relato descreve um paciente que apresentou dor insidiosa no quadril atribuída a artrite reumatoide, com desfecho fatal devido a doenças de base e complicações cirúrgicas.

A subestimação da dor no quadril, principalmente quando não há massa palpável, pode atrasar o diagnóstico.

## Linked entities

- **Diseases:** rheumatoid arthritis (MONDO:0008383), synovial sarcoma (MONDO:0010434)

## Full-text entities

- **Diseases:** Insidious Synovial Sarcoma of Bone (MESH:D013584), Rheumatoid Arthritis (MESH:D001172), soft tissue tumor (MESH:D012983), hip pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC11254417/full.md

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Source: https://tomesphere.com/paper/PMC11254417