# Pediatric discordant lymphoma with classic Hodgkin lymphoma in cervical lymph nodes and high-grade B-cell non-Hodgkin lymphoma in bone marrow: a case report from Pakistan

## TL;DR

A rare case of pediatric discordant lymphoma with two different lymphoma types in different body parts is reported from Pakistan.

## Contribution

This is a rare pediatric case report of discordant lymphoma with distinct lymphoma types in different anatomical sites.

## Key findings

- Classic Hodgkin lymphoma was found in cervical lymph nodes.
- High-grade B-cell non-Hodgkin lymphoma was detected in the bone marrow and abdominal mass.
- The case highlights the need for better understanding and treatment protocols for pediatric discordant lymphoma.

## Abstract

Discordant lymphoma (DL) is an uncommon condition in which two or more histologically different types of lymphomas are present at distinct anatomical sites in the same patient. Here, we report a case of a pediatric patient under 10 years old presenting with symptoms of general sickness with cervical lymphadenopathy, abdominal distension and an abdominal mass. Upon conducting investigations, classic Hodgkin lymphoma (CHL) was detected in the cervical lymph nodes, and high-grade B-cell non-Hodgkin lymphoma was detected in the bone marrow and abdominal mass. The patient was therefore diagnosed with DL. The boy was initially diagnosed with CHL but proceeded to have aggressive disease progression, due to which further workup was done. In the past, literature reports have been published for adult cases of DL, and currently, research is being conducted to formulate treatment protocols for it. However pediatric cases of DL remain widely undiscussed. Since we are dealing with a rare or widely underreported condition, we found it significant to elaborate on its clinical presentation, treatment plan, complications and prognosis.