# Radiotherapy-induced vitiligo in a patient with breast cancer, a case report

## TL;DR

A breast cancer patient developed vitiligo in the area treated with radiotherapy, possibly due to an autoimmune response.

## Contribution

This case report highlights a possible link between radiotherapy and vitiligo onset via the Koebner phenomenon.

## Key findings

- A breast cancer patient developed vitiligo 12 months after radiotherapy.
- The vitiligo appeared in the area treated with radiotherapy.
- The occurrence may be attributed to the Koebner phenomenon.

## Abstract

Vitiligo is a disease characterised by the autoimmune destruction of melanocytes, manifesting as depigmentation of the skin. We present the case of a female patient with a history of breast cancer who developed vitiligo in the area of the treatment field 12 months after the end of radiotherapy. It has been reported in the literature that vitiligo can occur in patients with a history of vitiligo after radiotherapy, attributable to the Koebner phenomenon, where some treatments can induce new vitiligo lesions in the patient.