# Fatal asphyxia due to large laryngeal granuloma

**Authors:** Ajay Kumar, Ravi Rautji, Asit Ranjan Mridha, Chittaranjan Behera

PMC · DOI: 10.4322/acr.2024.496 · 2024-06-14

## TL;DR

A rare case of fatal asphyxia caused by a large laryngeal granuloma following multiple intubations and a surgical procedure.

## Contribution

Reports a rare fatality due to laryngeal granuloma after surgical removal of a laryngeal polyp.

## Key findings

- Laryngeal granuloma can rarely lead to fatal asphyxia.
- The granuloma occurred after multiple intubations and a surgical procedure.
- Clinical awareness is crucial for early detection and management.

## Abstract

Laryngeal granuloma, vocal process granuloma, or post-intubation granuloma are benign, inflammatory lesions of the arytenoid cartilage vocal process. The etiology of laryngeal granulomas is multifactorial, such as chronic irritation due to endotracheal intubation, vocal cord injury or trauma, and gastroesophageal reflux disease. They can arise postoperatively after mucosal injury due to orotracheal intubation. Clinical manifestations include voice change and dyspnea, which may start one to four months after extubation and may rarely lead to asphyxia. We presented a case of death due to glottic granuloma occurring after a surgical procedure to remove a laryngeal polyp attributed to previous laryngeal injuries by multiple intubations.

## Linked entities

- **Diseases:** gastroesophageal reflux disease (MONDO:0007186)

## Full-text entities

- **Diseases:** dyspnea (MESH:D004417), death (MESH:D003643), mucosal injury (MESH:D052016), inflammatory lesions (MESH:D007249), laryngeal injuries (MESH:D061224), asphyxia (MESH:D001237), granuloma (MESH:D006099), Laryngeal granuloma (MESH:D006102), vocal cord injury or trauma (MESH:D013119), gastroesophageal reflux disease (MESH:D005764), laryngeal polyp (MESH:D011127)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11253911/full.md

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Source: https://tomesphere.com/paper/PMC11253911