# Empiric Treatment of Classical Pyoderma Gangrenosum in the Outpatient Setting: A Case Report

## TL;DR

This case report describes a 42-year-old man with classical pyoderma gangrenosum who was successfully treated with corticosteroids after failing antibiotic therapy.

## Contribution

The paper highlights the importance of early corticosteroid use in outpatient classical PG cases.

## Key findings

- The patient failed three antibiotic courses before responding to corticosteroids.
- Classical PG was diagnosed in an outpatient setting after excluding other conditions.
- Early corticosteroid treatment may improve outcomes in classical PG cases.

## Abstract

Pyoderma gangrenosum (PG) is a rare neutrophilic disorder that typically presents as painful, ulcerative lesions. It is a diagnosis of exclusion and is oftentimes associated with systemic conditions such as inflammatory bowel disease, rheumatoid arthritis, and other inflammatory conditions. PG remains difficult to diagnose, and a delay in recognizing the disease can contribute to appreciable morbidity in the population. Here, we present the case of a 42-year-old male with the classical subtype of PG in the outpatient clinic who failed three courses of antibiotics before responding to corticosteroids.