# Analysis of arterial blood gas values when discarding different volumes of blood samples in an arterial heparin blood collector during thoracoscopic surgery

## TL;DR

This study examines how discarding different volumes of blood affects arterial blood gas values during thoracoscopic surgery.

## Contribution

The study introduces a novel analysis of blood gas stability based on the volume of discarded blood samples.

## Key findings

- PaO2, PaCO2, and THbc values were more stable when the 4th and 5th ml of blood were used.
- Discarding the first 3 ml of blood may provide more accurate blood gas analysis without wasting samples.

## Abstract

Arterial blood gas analysis (ABGA) plays a vital role in emergency and intensive care, which is affected by many factors, such as different instrumentation, temperature, and testing time. However, there are still no relevant reports on the difference in discarding different blood volumes on ABGA values.

We enrolled 54 patients who underwent thoracoscopic surgery and analysed differences in blood gas analysis results when different blood volumes were discarded from the front line of the arterial heparin blood collector. A paired t test was used to compare the results of the same patient with different volumes of blood discarded from the samples. The difference was corrected by Bonferroni correction.

Our results demonstrated that the PaO2, PaCO2, and THbc were more stable in the 4th ml (PaO2 = 231.3600 ± 68.4878 mmHg, PaCO2 = 41.9232 ± 7.4490 mmHg) and 5th ml (PaO2 = 223.7600 ± 12.9895 mmHg, PaCO2 = 42.5679 ± 7.6410 mmHg) blood sample than in the 3rd ml (PaO2 = 234.1000 ± 99.7570 mmHg, PaCO2 = 40.6179 ± 7.2040 mmHg).

It may be more appropriate to discard the first 3 ml of blood sample in the analysis of blood gas results without wasting blood samples.

The online version contains supplementary material available at 10.1186/s12893-024-02501-4.