# Loss of Recurrent Laryngeal Papillomatosis following Postsurgical Treatment with dsRNA Interferon Inducer

**Authors:** Alina Sultanova, Liba Sokolovska, Maksims Cistjakovs, Andrejs Lifsics

PMC · DOI: 10.1155/2024/6044987 · Case Reports in Infectious Diseases · 2024-07-08

## TL;DR

A case report shows that a dsRNA-based antiviral drug helped cure a man's recurring laryngeal papillomatosis, a hard-to-treat benign tumor.

## Contribution

Demonstrates successful treatment of recurrent laryngeal papillomatosis using a dsRNA-based antiviral drug.

## Key findings

- The patient experienced complete resolution of laryngeal papillomatosis after dsRNA treatment.
- The dsRNA-based drug showed a positive response in treating a long-standing, recurring condition.
- This case suggests potential for dsRNA as an adjuvant therapy for laryngeal papillomatosis.

## Abstract

Laryngeal papillomatosis (LP) is the most common benign laryngeal tumor in children, but it can affect both children and adults. Although benign, this condition still remains hard to treat and negatively affects patient quality of life as it can spread to the adjacent respiratory tract, recurs, and requires repeated medical intervention. As the surgical removal of papillomas with the preservation of normal mucosa is the only standard of care, there is still no standard for adjuvant therapy. In this case report, we describe the course of recurrent laryngeal papillomatosis in a Caucasian male from 2009 to 2016 and the positive response to dsRNA-based antiviral drug treatment in the complete resolvement of the condition.

## Linked entities

- **Diseases:** laryngeal papillomatosis (MONDO:0023597)

## Full-text entities

- **Diseases:** benign laryngeal tumor (MESH:D007822), papillomas (MESH:D010212), LP (MESH:C537876)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC11250704/full.md

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Source: https://tomesphere.com/paper/PMC11250704