# Fifteen-Centimeter Giant Tamoxifen-Associated Endometrial Polyp Presenting With Constipation: A Case Report and Review of the Literature

## TL;DR

A 58-year-old woman with a history of tamoxifen use had a 15 cm endometrial polyp causing constipation, the largest such case reported.

## Contribution

This is the first documented case of a 15 cm giant endometrial polyp associated with tamoxifen use and presenting with constipation.

## Key findings

- A 15 cm endometrial polyp was identified in a patient with tamoxifen use and constipation.
- The case is the largest endometrial polyp reported in medical literature.
- Tamoxifen use is linked to the development of endometrial polyps.

## Abstract

Endometrial polyps are benign disorganized growth of endometrial glands and stroma in the uterine cavity. They are associated with subfertility, abnormal uterine bleeding, and tamoxifen use. While most polyps are smaller than 2 cm in size, rare giant polyps can cause concerns over malignancy. We report a case of a 15 cm giant endometrial polyp in a 58-year-old woman with a history of tamoxifen use who presented with an uncommon complaint of constipation. Additionally, a literature review of giant endometrial polyp cases is presented. This case represents the largest reported endometrial polyp to date.