Serum vitamin D and PSA in elderly men in Amirkola

TL;DR

This study found no significant link between vitamin D levels and PSA in elderly men in Amirkola, but noted widespread vitamin D deficiency.

Contribution

The study provides new local data on vitamin D and PSA in elderly men, highlighting a lack of correlation and prevalent vitamin D deficiency.

Findings

No significant relationship was found between vitamin D and PSA levels (P = 0.16).

Age was significantly associated with increased PSA levels (P = 0.001).

Most elderly participants had vitamin D deficiency.

Abstract

Vitamin D is a modifiable risk factor in cancer and prostate diseases. In this study, we investigate the relationship between vitamin D and serum PSA in elderly men of Amirkola City.

The current cross-sectional descriptive study was conducted on elderly men participating in the cohort study in Amirkola. Demographic information including age, sex, marital status and occupation were recorded and blood samples (5 cc of blood) were taken to measure PSA and vitamin D. A p -value less than 0.05 is statistically significant.

After applying the inclusion and exclusion criteria, 837 elderly men with mean age of 69.99 ± 7.72 years were included in the study. In terms of marital status, 779 (93.1%) were married and 59 (6.9%) were single. In the study of employment status, 476 (56.9%) self-employed, 331 (439.5%) retired, 8 (1.0 %) housewives, 14 (1.7%) unemployed and 8 (1.0 %) They were in an unknown situation. The mean level of vitamin D was 31.94 ± 28.57 ng / mL and the mean level of PSA was 1.94 ± 3.28 ng / dL. No significant relationship was found between vitamin D level and serum PSA in Pearson Correlation test (P = 0.16). Among the other variables studied, only age was related to PSA levels and PSA level increased with age (P = 0.001).

No significant relationship was found between PSA serum level and vitamin D level, but the existence of vitamin D deficiency in most of the elderly studied needs attention.

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